{"created":"2023-05-15T14:41:44.891287+00:00","id":57237,"links":{},"metadata":{"_buckets":{"deposit":"93b537d6-0d1d-404f-8d0a-55a0787c0928"},"_deposit":{"created_by":1,"id":"57237","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"57237"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00057237","sets":["11"]},"author_link":["579033","579034"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"36","bibliographicPageStart":"29","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Hormone Frontier in Gynecology"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"乳腺の内部ではさまざまな局所調節因子がネットワークを形成している。たとえば発達期の乳管上皮の成長や腺房形成は、ホルモンという外部シグナルに応答しながら、局所で産生されるサイトカインや成長因子によって調節されている。逆に上皮組織が混みすぎないようにする仕組みも、局所の成長因子に依っている。また、授乳期の母乳の産生量、成分そして分泌期間も、乳腺内の状態を監視し、適切な局所因子を動員するシステムによって調節されている。さらに、これらの局所調節因子が乳癌の発症に係わっていることも明らかになりつつある。","subitem_description_type":"Abstract"}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1340-220X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"今岡, 達彦"}],"nameIdentifiers":[{"nameIdentifier":"579033","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今岡 達彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"579034","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"乳腺の局所調節ネットワーク　―発生・授乳の調節から発癌まで―","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"乳腺の局所調節ネットワーク　―発生・授乳の調節から発癌まで―"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-01-26"},"publish_date":"2007-01-26","publish_status":"0","recid":"57237","relation_version_is_last":true,"title":["乳腺の局所調節ネットワーク　―発生・授乳の調節から発癌まで―"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:29:20.073468+00:00"}