@article{oai:repo.qst.go.jp:00057053,
 author = {Girard, F and Suhara, Tetsuya and Sassa, Takeshi and Okubo, Yoshiro and Obata, Takayuki and Ikehira, Hiroo and Sudo, Yasuhiko and Koga, Masahisa and Yoshida, Katsuya and et.al and 須原 哲也 and 佐々 毅 and 大久保 善朗 and 小畠 隆行 and 池平 博夫 and 古賀 雅久 and 吉田 勝哉},
 journal = {Recent Advances in Biomedical Imaging (International Congress Series ; no. 1127)},
 month = {},
 note = {Backgraound. Lithium is widely used in the treatment of mood disorders, but little is known about its mechanisum of action. Repartition of lithium in the brain could help to the understanding of this mechanism, and therefore lead to a better individualized therapy.
 Methods. Direct 7Li spectroscopic imaging on humans has been developed and performed on a clinical magnetic resonance system. Spectroscopic images (SI) on phantoms have been acquired as a first step to validate the method, and in vivo images of human brains have been acquired afterwards. A phosphorus volume head coil was used for lithium experiments, with parameters optimized for this purpose.
 Results. SI of human brain has been realized, and our results are consistent with previous studies. They show little variations of the repartition of lithium inside the brain.
 Conclusion. Our images show the feasibility of these studies. Possible evolutions include a better resolution of the images, a better localization, and a quantitative analysis of the results.},
 pages = {225--232},
 title = {Direct two-dimensional spectroscopic imaging of lithium},
 year = {1997}
}