{"created":"2023-05-15T14:41:18.926558+00:00","id":56654,"links":{},"metadata":{"_buckets":{"deposit":"bae77227-7983-4269-830d-3e20c5b1a515"},"_deposit":{"created_by":1,"id":"56654","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"56654"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00056654","sets":["11"]},"author_link":["576603","576605","576604","576602"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"34","bibliographicPageStart":"34","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"インナービジョン"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"記憶・感情などを司る中枢神経系（脳）におよぼす放射線の影響は，脳腫瘍および白血病などの放射線治療に伴う副作用や，原子力災害による胎児期被ばくの際において，重大な関心事の一つである。現在，小児性脳腫瘍や白血病に対する放射線治療は，Ｘ線照射範囲を全脳まで拡大して予防照射を行い，その予後や生存率は改善されつつある。一方，生存率の改善に伴い治療後の晩発性知能・言語障害や精神発達障害の併発が報告されるようになり，今後その障害をいかにして低く抑えるかが課題とされている。\n　本研究では，放射線による高次脳機能障害の特徴や障害部位，その障害のメカニズムについて明らかにするため，生体内の標的組織（腫瘍）に線量を集中することが可能な炭素線を利用応用し，放射線脳局所照射モデルを用いて記憶・学習障害の解析を行った。またＸ線を利用した胎児期被ばくモデルよる記憶・学習におよぼす影響とその機序についても検討を行った。","subitem_description_type":"Abstract"}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0913-8919","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安藤, 興一"}],"nameIdentifiers":[{"nameIdentifier":"576602","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高井, 伸彦"}],"nameIdentifiers":[{"nameIdentifier":"576603","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安藤 興一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"576604","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高井 伸彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"576605","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"放射線照射による脳機能障害とその防護","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"放射線照射による脳機能障害とその防護"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-08-11"},"publish_date":"2004-08-11","publish_status":"0","recid":"56654","relation_version_is_last":true,"title":["放射線照射による脳機能障害とその防護"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:35:52.475237+00:00"}