@article{oai:repo.qst.go.jp:00056107, author = {斎藤, 克代 (高崎健康福祉大) and 舟山, 知夫 and 横田, 裕一郎 and 小林, 泰彦 and 舟山 知夫 and 横田 裕一郎 and 小林 泰彦}, journal = {QST Takasaki Annual  Report 2016}, month = {Mar}, note = {We demonstrate that the use of histone deacetylase inhibitors (HDACi) could sensitize refractory tumor cells well for the heavy-ion therapy. B16F10 murine melanoma cells were treated with several HDACis and followed by irradiations. Thereafter, immunofluorescence microscopy ofγH2AX were carried out. Foci size of γH2AX in γ-ray irradiated cells became bigger by pretreatment with HDACis, although foci size of γH2AX in heavy-ion irradiated cells was almost unchanged by pretreatment with HDACis.}, pages = {86--86}, title = {Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (V)}, year = {2018} }