@article{oai:repo.qst.go.jp:00056081,
 author = {Kato, Yuichi and Ho, Shih-Hsin and Ogino, Chiaki and Hasunuma, Tomohisa and 佐藤, 勝也 and 大野, 豊 and Kondo, Akihiko and 佐藤 勝也 and 大野 豊},
 journal = {QST Takasaki Annual Report 2016},
 month = {Mar},
 note = {High salinity stimulates lipid accumulation in the green microalga Chlamydomonas sp. JSC4 by activating a starch-to-lipid biosynthesis switching mechanism. The aim of this study was to improve JSC4 algal biomass production under high salinity conditions by breeding a salt-resistant strain. Microalgal cells seeded on agar plates were irradiated with 50 Gy of the carbon ion beams at TIARA. After long-term and continuous cultivation with high salinity, the salt-resistant strain (KHI) that grow well even in the presence of 7% sea salt was successfully obtained. Under 7% sea salt, the KHI showed the biomass productions, while that of JSC4 did not. The KHI showed higher starch and lipid contents under 7% sea salt, , while that of JSC4 also did not. These results suggest that high salinity stress, not the salinity condition itself, is important for activating lipid accumulation mechanisms in microalgae.},
 title = {Mutational Breeding of Salt-Resistant Chlamydomonas sp. Strains Reveals Salinity Stress-Activated Starch-to-Lipid Biosynthesis Switching},
 year = {2018}
}