@article{oai:repo.qst.go.jp:00055931, author = {Baumstark-Khan, Christa and F, Spitta Luis and E, Hellweg Christine and Henschenmacher, Sebastian and Bernd, Diegeler Sebastian and Konishi, Teruaki and Uchihori, Yukio and 小西 輝昭 and 内堀 幸夫}, issue = {HIMAC-141}, journal = {2013 Annual Report of the Research Project with Heavy Ions at NIRS-HIMAC}, month = {Oct}, note = {For sake of better risk assessment for the astronaut, the cellular response to such ionizing radiation qualities, as predominate in Space, needs to be better understood. Cell cycle control as a central element in DNA damange response will be investigated as it is a central switch for cellular decision making between life and death. Thus cell death bypass mechnisms in DNA damage response of mammalian cells will be investigated after heavy ion exposure relevant for the Space radiation environment. The RBE-LET dependency will be determined for different biological endpoints. Of special interest are the activation of transcription factors and the identification of genes expressed in DNA damange response after high LET exposure.}, pages = {110--111}, title = {Cell death bypass mechanisms in DNA damage response of mammalian cells after exposure with heavy ions relevant for Space radiation environment}, volume = {NIRS-M-273}, year = {2014} }