{"created":"2023-05-15T14:40:32.001645+00:00","id":55613,"links":{},"metadata":{"_buckets":{"deposit":"2778fe60-5da8-43d2-8e6a-0ad6a74d4d16"},"_deposit":{"created_by":1,"id":"55613","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"55613"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00055613","sets":["7"]},"author_link":["568996","568995","568997","568994","568998","568999"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"HIMAC-129","bibliographicPageEnd":"78","bibliographicPageStart":"77","bibliographicVolumeNumber":"NIRS-M-214","bibliographic_titles":[{"bibliographic_title":"Annual Report of the Research Project with Heavy Ions at NIRS-HIMAC"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Protection against heavy ion-induced genotoxicity has not been well investigated. N-Acetyl Cysteine (NAC) is a well-known, nontoxic derivative of L-Cysteine that has antioxidant properties. Here we measured the ROS amounts induced by neon ion exposure in vitro both with and without NAC supplementation. Subsequently, we measured the protective effect of NAC on neon ion mutation induction. NAC protected against neon ion ROS induction and offered mixed protection against genotoxicity.","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"放医研"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hafer, Kurt"}],"nameIdentifiers":[{"nameIdentifier":"568994","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Konishi, Teruaki"}],"nameIdentifiers":[{"nameIdentifier":"568995","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Robert, Schiestl"}],"nameIdentifiers":[{"nameIdentifier":"568996","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｈａｆｅｒ Ｋｕｒｔ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"568997","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小西 輝昭","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"568998","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｒｏｂｅｒｔ Ｓｃｈｉｅｓｔｌ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"568999","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The role of high LET radiation induced persistent oxidative stress and nucleotide excision repair on genomic instability in mammalian cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The role of high LET radiation induced persistent oxidative stress and nucleotide excision repair on genomic instability in mammalian cells"}]},"item_type_id":"10004","owner":"1","path":["7"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-09-03"},"publish_date":"2008-09-03","publish_status":"0","recid":"55613","relation_version_is_last":true,"title":["The role of high LET radiation induced persistent oxidative stress and nucleotide excision repair on genomic instability in mammalian cells"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:47:27.182808+00:00"}