@article{oai:repo.qst.go.jp:00055613, author = {Hafer, Kurt and Konishi, Teruaki and Robert, Schiestl and Hafer Kurt and 小西 輝昭 and Robert Schiestl}, issue = {HIMAC-129}, journal = {Annual Report of the Research Project with Heavy Ions at NIRS-HIMAC}, month = {Jun}, note = {Protection against heavy ion-induced genotoxicity has not been well investigated. N-Acetyl Cysteine (NAC) is a well-known, nontoxic derivative of L-Cysteine that has antioxidant properties. Here we measured the ROS amounts induced by neon ion exposure in vitro both with and without NAC supplementation. Subsequently, we measured the protective effect of NAC on neon ion mutation induction. NAC protected against neon ion ROS induction and offered mixed protection against genotoxicity.}, pages = {77--78}, title = {The role of high LET radiation induced persistent oxidative stress and nucleotide excision repair on genomic instability in mammalian cells}, volume = {NIRS-M-214}, year = {2008} }