@article{oai:repo.qst.go.jp:00055387,
 author = {柳, 剛 and 鎌田, 正 and 辻, 比呂志 and 辻井, 博彦 and 柳 剛 and 鎌田 正 and 辻 比呂志 and 辻井 博彦},
 journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書},
 month = {Apr},
 note = {Pupose:The aim of this study is to evaluate the clinically relevant parameters for skin reactions using DSH and DVH (dose surface  histogram and dose volume histogram) in carbon ion radiotherapy of bone and soft tissue sarcoma.
Materials and methods:For the sake of accuracy and simplicity, 35 patients were analyzed for acute skin reactions and 27 for late skin reactions among the patient pool described at the report last year. Both intebral DVH and DSH were obtained in all the patients, and the correlation between the clinical skin reactions and these parameters were investigated. Some of the pretreatment variables thought to be relenvant to skin reactions were also assessed.
Results:According to the univarriate analysis, the total prescribed dose, DSH, primary tumor site (sacrum versus the other),the distance between skin surface and tumor edge, and DVH were statistically significant relative to the development of acute skin reactions. To the late, the prescribed dose, DSH, DVH, and the distance between skin surface and tumor were statistically significant. The result of multivariate analysis was that the DSH was a statistically significant factor for the acute skin reactions.
Conclusions:DSH is a useful parameter to predict the acute skin reactions.},
 pages = {33--35},
 title = {骨軟部腫瘍の皮膚反応に対するDVH分析},
 year = {2004}
}