@article{oai:repo.qst.go.jp:00055243,
 author = {伊藤, 敦 and 平山, 亮一 and 村山, 千恵子 and 古澤, 佳也 and 伊藤 敦 and 平山 亮一 and 村山 千恵子 and 古澤 佳也},
 journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書},
 month = {Apr},
 note = {Production of 8-hydroxy-2'-deoxyguanosine (8-OH-dG) from 2'-deoxyguanosine (dG) was examined upon irradiation with X-rays, carbon, neon or silicon ions. The LETs of heavy ions ranged from 20 to 300 keV/um. dG in aqueous solution was irradiated under air-saturated or hypoxic condition. Under the air-saturated condition, the yield of 8-OHdG decreased with increasing LET. The decreasing rate nearly paralleled with the decrease in G value of OH-radical production. On the other hand, under the hypoxic condition, the decreasing rate of 8-OH-dG yield with increasing LET was significantly lower than that obtained under the air-saturated condition. These results are consistent with the hypothesis of "oxygen-in-the-track model" previously proposed by Baverstock and others. Further research in the 8-OHdG production in cellular system is in progress.},
 pages = {119--120},
 title = {重粒子線が生成する細胞中のＤＮＡ損傷と染色体異常},
 volume = {2002},
 year = {2003}
}