@article{oai:repo.qst.go.jp:00055214,
 author = {田内, 広 and 笠井, 清美 and 古澤, 佳也 and 安藤, 興一 and 小松, 賢志 and 田内 広 and 笠井 清美 and 古澤 佳也 and 安藤 興一},
 journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書},
 month = {Oct},
 note = {A novel hyper - sensitive mutation detection system, which uses hamster fibroblast cells carrying a normal human X-chromosome, has been developed. The system is 100-fold more sensitive than the conventional system using an internal Hprt gene. This suggests that the system appears to be able to detect a wide spectrum of mutations, even mutations affecting the expression of important genes in neighborhood of the Hprt gene. A lower limit of radiation dose for mutation induction with the system was found to be around 0.1 Gy. Using this system, we started to investigate low dose-rate effects of heavy particle beam (carbon 290 MeV/u beam) with different LETs.},
 pages = {117--118},
 title = {HPRT欠損突然変異高感度検出系を用いた突然変異スペクトルのLET依存性解明},
 volume = {2002},
 year = {2003}
}