@article{oai:repo.qst.go.jp:00055111, author = {田内, 広 and 笠井, 清美 and 古澤, 佳也 and 安藤, 興一 and 松浦, 伸也 and 小松, 賢志 and 田内 広 and 笠井 清美 and 古澤 佳也 and 安藤 興一}, journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書}, month = {Apr}, note = {A new version of hyper-sensitive detection system for somatic mutation by radiation is under construction. The system uses Hprt deficient mouse fibroblast cells which carrying a normal human X-chromosome. To prevent the spontaneous loss of whole human X-chromosome, a neo selection marker was transfected into the mouse-human X hybrid cells. The system must be useful to detect wide spectrum of Hprt-deficient mutation even if it affects on the important genes in nabor of Hprt.}, pages = {116--117}, title = {HPRT欠損突然変異高感度検出系を用いた突然変異スペクトルのLET依存性解明}, volume = {2000}, year = {2001} }