@article{oai:repo.qst.go.jp:00055086,
 author = {田内, 広 and 笠井, 清美 and 白石, 貴博 and 古澤, 佳也 and 安藤, 興一 and 小松, 賢志 and 田内 広 and 笠井 清美 and 古澤 佳也 and 安藤 興一},
 journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書},
 month = {Oct},
 note = {A novel hyper-sensitive detection system was developed to detect Hprt-deficient mutations. The system, which uses hamster fibroblast cells carrying a normal human X-chromosome, has been found to be 100-fold more sensitive for detecting mutations induced by gamma-rays than the conventional system using an internal Hprt gene. This suggests that the system appears to be able to detect a wide spectrum of mutations, even mutations affecting the expression of important genes in neighborhood of the Hprt gene. Using the system, we have tested the lower limit dose for detection of significant mutation induction by carbon 290 MeV/u beam.},
 pages = {114--115},
 title = {HPRT欠損突然変異高感度検出系を用いた突然変異スペクトルのLET依存性解明},
 volume = {2001},
 year = {2002}
}