@inproceedings{oai:repo.qst.go.jp:00054549, author = {Maruyama, Masahiro and Shimada, Hitoshi and Ming-Rong, Zhang and Suhara, Tetsuya and Higuchi, Makoto and Maruyama, Masahiro and Shimada, Hitoshi and Ming-Rong, Zhang and Suhara, Tetsuya and Higuchi, Makoto}, book = {NIRS Annual Report 2013}, month = {Nov}, note = {Intracellular inclusions of pathological tau fibrils are hallmark lesions in Alzheimer’s disease (AD) and associated tauopathies, and there has been a growing interest in the mechanistic links between fibrillar tau accumulation and neuronal deterioration. Characteristic symptoms of tauopathies are known to be associated with regional distribution of fibrillary tau lesions. In-vivo tau imaging would accordingly facilitate precise clinical diagnosis of tauopathies and objective staging of the disease in living patients on a neuropathological basis. At this time, there has been no confirmation of an imaging agent which is suitable for tau inclusions not only for AD but also non-AD tauopathies by positron emission tomography (PET).}, pages = {46--7}, publisher = {national institute of radiological sciences}, title = {Visualization of tau pathology in living mouse model and human tauopathies including Alzheimer’s disease}, year = {2014} }