@inproceedings{oai:repo.qst.go.jp:00054516, author = {Atanasova, Severina and Lazarova, Desislava and Pancheva, Nikolova-Lefterova Biliana and Zhelev, Zhivko and I.Tsoneva and Aoki, Ichio and Bakalova-Zheleva, Rumiana and アタナソヴァ セヴァリナ and ラザロヴァ デシスラヴァ and ニコロヴァレフタロヴ� .咼螢▲福� and Zhelev Zhivko and 青木 伊知男 and バカロバ ルミアナ}, book = {ANTICANCER RESEARCH}, month = {Oct}, note = {The present study was designed to investigate whether electroporation can facilitate the delivery of drugs inside tumors, using quantum dot (QD)-loaded polymersomes as a model. The main goal was to increase the local concentration of anticancer drugs avoiding side-effects. The experiments were performed on colon-cancer grafted mice (Balb/c) using Maestro EX Imaging System. Electroporation facilitated the delivery of nanoparticles inside the tumor. A significant difference in the fluorescence intensity between electroporated and non-electroporated mice was observed in cancer area even 24 hours after treatment with nanoparticles. The data suggest that electro-assisted delivery of size-controlled long-circulating polymersomes in cancer is a promising therapeutic strategy, especially for treatment of solid tumors.}, pages = {5819--5821}, title = {In vivo visualization of electro-assisted delivery of nanoparticles using optical imaging}, volume = {34}, year = {2014} }