{"created":"2023-05-15T14:39:40.501595+00:00","id":54488,"links":{},"metadata":{"_buckets":{"deposit":"a014d4c2-e43c-48ca-8cba-4b840b2ba2ab"},"_deposit":{"created_by":1,"id":"54488","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"54488"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00054488","sets":["2"]},"author_link":["556542","556545","556541","556549","556547","556550","556548","556546","556544","556543"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"S1","bibliographicPageStart":"i113","bibliographicVolumeNumber":"55","bibliographic_titles":[{"bibliographic_title":"Journal of Radiation Research"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The microbeam irradiation system (single-particle irradiation system to cell, acronym as SPICE) at the National Institute of Radiological Sciences (NIRS), Japan, was employed to irradiate dechorionated embryos of the zebrafish, Danio rerio, at 5 h post-fertilization (hpf) by protons each having an energy of ∼3.4 MeV. Either 1 or 10 positions on the cells were irradiated with different number of protons. The levels of apoptosis in zebrafish embryos at 25 hpf were quantified through terminal dUTP transferase-mediated nick end-labeling assay. Triphasic dose–esponses were obtained (Fig. 1), including (i) a subhormetic zone with an increase in apoptotic signals for a small number of irradiated protons per position, (ii) a hormetic zone with a reduction in the apoptotic signals below the spontaneous level for a larger number of irradiated protons per position and (iii) a toxic zone with an increase in apoptotic signals again if the number of irradiated protons per position was further increased. ","subitem_description_type":"Abstract"}]},"item_10003_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford Journals, Oxford University Press"}]},"item_10003_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"doi: 10.1093/jrr/rrt164","subitem_relation_type_select":"DOI"}}]},"item_10003_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://jrr.oxfordjournals.org/cgi/content/abstract/rrt164?"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://jrr.oxfordjournals.org/cgi/content/abstract/rrt164?","subitem_relation_type_select":"URI"}}]},"item_10003_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0449-3060","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wing, Yan Choi  Viann"}],"nameIdentifiers":[{"nameIdentifier":"556541","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yuen, Ping Ng Candy"}],"nameIdentifiers":[{"nameIdentifier":"556542","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Alisa"}],"nameIdentifiers":[{"nameIdentifier":"556543","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Konishi, Teruaki"}],"nameIdentifiers":[{"nameIdentifier":"556544","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oikawa, Masakazu"}],"nameIdentifiers":[{"nameIdentifier":"556545","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Han, Cheng  Shuk"}],"nameIdentifiers":[{"nameIdentifier":"556546","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kwan, Ngok Yu Peter"}],"nameIdentifiers":[{"nameIdentifier":"556547","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小林 亜利紗","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"556548","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小西 輝昭","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"556549","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"及川 将一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"556550","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"Response of 5 hpf zebrafish embryos to low-dose microbeam protons","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Response of 5 hpf zebrafish embryos to low-dose microbeam protons"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-03-06"},"publish_date":"2014-03-06","publish_status":"0","recid":"54488","relation_version_is_last":true,"title":["Response of 5 hpf zebrafish embryos to low-dose microbeam protons"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:00:21.404643+00:00"}