@inproceedings{oai:repo.qst.go.jp:00054395, author = {Tsuji, Hiroshi and Mizoguchi, Nobutaka and Toyama, Shingo and Kamada, Tadashi and Tsujii, Hirohiko and 辻 比呂志 and 溝口 信貴 and 戸山 真吾 and 鎌田 正 and 辻井 博彦}, book = {NIRS-ETOILE Joint Symposium on Carbon Ion Radiotherapy}, issue = {NIRS-M-243}, month = {Nov}, note = {Abstract Therapeutic outcome of hypofractionated conformal carbon ion radiotherapy towards localized prostate cancer was investigated. We analyzed the biochemical relapse-free rate of 1,084 cases whic were observed for 6 months or more after carbon ion radiotherapy at the time of February 2011, also we analyzed survival rate, and the incidence of toxicity.l 5-year biochemical relapse-free rate of whose cases was 90.6%. The Gleason score, PSA value and clinical stage were the significant prognostic factor of relapse-free rate. The difference of relapse-free rate by method of fractionation (20 fractions and 16 fractions) was not found. None but one out of 1,005 cases who were followed up at least 1 year developed grade 3 lower urological impairment, and incidences of grade 2 were 5.6% in lower urinary tract and 2.3% in the rectum, respectively. Furthermore, in the 16 fractions, the toxicity incidence was lower than 20 fractions. Accordingly, hypofractionation made it possible to reduce the toxicity incidence without reducing the rlapse-free rate.}, pages = {66--72}, publisher = {National Institute of Radiological Sciences}, title = {Carbon Ion Radiotherapy for Prostate Cancer}, volume = {2}, year = {2011} }