{"created":"2023-05-15T14:39:36.271352+00:00","id":54393,"links":{},"metadata":{"_buckets":{"deposit":"ab98113d-6446-4037-bc1c-ac5fdba89abd"},"_deposit":{"created_by":1,"id":"54393","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"54393"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00054393","sets":["2"]},"author_link":["555602","555606","555604","555605","555603","555601"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"15S","bibliographicPageEnd":"562S","bibliographicPageStart":"562S","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"International Journal of Clinical Oncology"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Carbon ion radiotherapy for bone and soft tissue sarcomas. \nT. Kamada, R. Imai, H. Tsujii, H. Tsuji, I. Serizawa; National Institute of Radiological  Sciences, Chiba, Japan\nBackground: Carbon ion radiotherapy showed promising clinical outcomes in 57 patients with bone and STS during the phase I study (Kamada, JCO 22 4466-4471, 2002). This phase II study was planned thereafter.\nMethods: From April 2000 to February 2007, 301 lesions of 282 patients with bone and STS not suited for surgical resection were enrolled in this phase II study. A total dose of 64.0 GyE in 16 fractions over 4 weeks was indicated for 15 lesions, that of 70.4 GyE for 276 and remaining 10 receiving 73.6 GyE. Mean age was 52 yrs, (range 12-85); site of origin was the pelvis in 74%, spine or para-spinous softtissue in 20%, extremities in 5%; bone primarywas in 78% and softtissue in 22%; pathologic subtype in bone sarcoma was chordoma in 42%, chondrosarcoma in 21%, osteosarcoma in 21%; pathologic subtype in STS was MFH in 23%, MPNST in 21%, synovial sarcoma in 13%. \nResults: The 3- and 5-year overall actuarial survival rates were 68% (95% Cl, 61%-75%) and 52% (95% Cl, 43%-61%), respectively, and the actuarial overall local control rates were 85% (95% Cl, 80%- 90%), and 81% (95% Cl, 74%-88%) at 3 years and 5 years of follow-up, respectively. Overall toxicity was acceptable, with 2% skin/soft tissue late G3/4 toxicity. \nConclusions: Carbon ion radiotherapy shows a substantial local control in the patients with bone and soft tissue sarcomas not suited for surgical resection with acceptable morbidity.","subitem_description_type":"Abstract"}]},"item_10003_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-9625","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"555601","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imai, Reiko"}],"nameIdentifiers":[{"nameIdentifier":"555602","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Serizawa, Itsuko"}],"nameIdentifiers":[{"nameIdentifier":"555603","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"555604","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 礼子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"555605","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"芹澤 慈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"555606","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"Carbon ion radiotherapy for bone and soft tissue sarcomas","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon ion radiotherapy for bone and soft tissue sarcomas"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-14"},"publish_date":"2013-11-14","publish_status":"0","recid":"54393","relation_version_is_last":true,"title":["Carbon ion radiotherapy for bone and soft tissue sarcomas"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:01:28.163027+00:00"}