{"created":"2023-05-15T14:39:30.932814+00:00","id":54272,"links":{},"metadata":{"_buckets":{"deposit":"d4ab9ed3-a846-4615-9a0e-5218974b1fe0"},"_deposit":{"created_by":1,"id":"54272","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"54272"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00054272","sets":["2"]},"author_link":["554353","554355","554356","554354","554347","554358","554351","554349","554348","554350","554357","554352"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3 supplement","bibliographicPageEnd":"S308","bibliographicPageStart":"S308","bibliographicVolumeNumber":"78","bibliographic_titles":[{"bibliographic_title":"International Journal of Radiation Oncology Biology Physics"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose/Objective(s)\nTo evaluate the efficacy and complication of carbon ion radiotherapy in treating patients affected by lymph node recurrence from resected colorectal cancer.\nMaterials/Methods\nBetween December 2004 and December 2009, a total of 26 patients with 34 lymph node recurrences from resected colorectal cancer were treated with carbon ion radiotherapy. Lymph node recurrence from colorectal cancer without distant metastasis was confirmed by CT, MRI, and carbon-11 methionine positron emission tomography findings. The subsite distribution was paraaortic area, 59% (n = 20); iliac, 26% (n = 9); mediastinal, 9% (n = 3); inguinal, 3% (n = 1); and aortoiliac, 3% (n = 1). Twenty-one of 26 patients had undergone multimodality therapy for locoregional and/or metastatic recurrence. The median age was 55 years (range, 38-85). The doses were escalated from 48 GyE to 52.8 GyE and were delivered in 12 fractions/3weeks. The median follow-up period was 16.8 months.\nResults\nAll patients completed the scheduled treatment course. No patient experienced acute or late morbidity of grade 3 or higher. Tumor response was evaluated in 34 lesions. Complete response (CR) was observed in 14 lesions and partial response (PR) in 13. Two lesions remained stable disease. The overall tumor response rate (CR+PR) was 79%. Remarkable anti-tumor effects were observed. The local control rates were 91% and 72% at 1 year and at 3 years, respectively. There is no local recurrence in the lesions receiving 50.4 GyE or more. The overall survival rates were 90% and 62% at 1 year and at 3 years, respectively.\nConclusions\nCarbon ion radiotherapy seems to be a safe and effective modality in the management of lymph node recurrence from resected colorectal cancer, providing good local control and offering a survival advantage without unacceptable morbidity.","subitem_description_type":"Abstract"}]},"item_10003_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0360-3016","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shinoto, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"554347","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Shigeru"}],"nameIdentifiers":[{"nameIdentifier":"554348","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasuda, Shigeo"}],"nameIdentifiers":[{"nameIdentifier":"554349","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imada, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"554350","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"554351","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"554352","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠藤 誠","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554353","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 滋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554354","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安田 茂雄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554355","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今田 浩史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554356","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554357","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"554358","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"Clinical Results of Carbon Ion Radiotherapy for Lymph Node Recurrence from Resected Colorectal Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical Results of Carbon Ion Radiotherapy for Lymph Node Recurrence from Resected Colorectal Cancer"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-12-14"},"publish_date":"2010-12-14","publish_status":"0","recid":"54272","relation_version_is_last":true,"title":["Clinical Results of Carbon Ion Radiotherapy for Lymph Node Recurrence from Resected Colorectal Cancer"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:02:53.424822+00:00"}