{"created":"2023-05-15T14:39:28.015516+00:00","id":54206,"links":{},"metadata":{"_buckets":{"deposit":"94f824db-2b31-4954-89fb-e057f63f87e9"},"_deposit":{"created_by":1,"id":"54206","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"54206"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00054206","sets":["2"]},"author_link":["553428","553427","553441","553436","553430","553432","553431","553435","553437","553434","553433","553438","553429","553424","553440","553425","553426","553439"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-08","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"82","bibliographicPageStart":"75","bibliographicVolumeNumber":"NIRS-M-225","bibliographic_titles":[{"bibliographic_title":"NIRS-IMP Joint Symposium on Carbon Ion Therapy"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Analysis on the results of hypofractionated conformal carbon ion radiotherapy (C-ion RT) for localized prostate cancer was performed, with regard to normal tissue morbidity, biochemical relapse-free rate (bNED), and patient survival. Methods and Materials:  Seven hundreds and forty prostate cancer patients who received C-ion RT established through two preceding dose-escalation studies were analyzed in regard to toxicity, survival, and bNED.  Results: Concerning radiation morbidity, no grade 3 or higher toxicities were observed either in the rectum or genitourinary system (GU), and incidences of grade 2 rectum and GU morbidity were only 1.9% and 4.8%, respectively.  Incidence of late GU toxicity in the patients treated with C-ion RT of 16 fractions was lower than that of 20 fractions. Overall bNED at 5 years was 90.2%, with only four local recurrences. The bNED of the C-ion RT of 16 fractions was comparable to that of 20 fractions. Gleason's score, T-stage, and initial PSA were significant prognostic factors for bNED, and T-stage and initial PSA were also significant prognostic factors for overall survival rate. The duration of hormonal therapy also had an impact on biochemical control in high-risk patients, but it appeared possible to apply C-ion RT with short-course hormonal therapy to intermediate-risk patients. Conclusion: C-ion RT with the established dose fractionation regimen yielded satisfactory bNED with very few local recurrences, and with minimal morbidity. C-ion RT of 16 fractions could offer even lower incidence of GU toxicity than that of 20 fractions.","subitem_description_type":"Abstract"}]},"item_10003_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"National Institute of Radiological Science"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"553424","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okada, Tohru"}],"nameIdentifiers":[{"nameIdentifier":"553425","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugahara, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"553426","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Hiroyuki"}],"nameIdentifiers":[{"nameIdentifier":"553427","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Hitoshi"}],"nameIdentifiers":[{"nameIdentifier":"553428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"553429","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mizoe, Junetsu"}],"nameIdentifiers":[{"nameIdentifier":"553430","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanai, Tatsuaki"}],"nameIdentifiers":[{"nameIdentifier":"553431","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"553432","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 比呂志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553433","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡田 徹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553434","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅原 信二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553435","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 弘之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553436","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553437","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江 純悦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金井 達明","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"553441","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"Carbon Ion Radiotherapy for Prostate Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon Ion Radiotherapy for Prostate Cancer"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-03-05"},"publish_date":"2010-03-05","publish_status":"0","recid":"54206","relation_version_is_last":true,"title":["Carbon Ion Radiotherapy for Prostate Cancer"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:03:40.694509+00:00"}