@inproceedings{oai:repo.qst.go.jp:00054129,
 author = {Matsushita, Satoru and Nishikawa, Tetsu and 松下 悟 and 西川 哲},
 book = {Experimental Animals},
 issue = {3 Supplement},
 month = {Apr},
 note = {A case of an allergic reaction caused by a mouse bite occurred in our organization in 2008. Since then, we have implemented measures to prevent such incidents from occurring again.
NIRS has eleven animal facilities, where 45,000 mice, 5,000 rats and 100 monkeys are housed. A staff of 280 researchers and caretakers have contact with the laboratory animals.
The occupational health and safety monitoring of these employees requires periodical submission of a health questionnaire, and serum sampling for cryopreservation before and after working with laboratory animals.  The health questionnaire asks about symptoms respondents are concerned about, and allergic symptoms, such as disorders of the eye (itchy, hyperemia), nose (watery, rhinitis), and skin (swelling, rash), as well as asthma and hives. Less than 3 % of approximately 200 of those employees per year have reported allergic symptoms over the last 9 years.  A total of approximately 100 occupational health and safety accidents have occurred over the last 11 years in our institute, and 25 % of those were related to laboratory animal experiments.  We have experienced incidences of anaphylaxis due to skin puncture with a syringe used on a rat in 1998, and severe allergic symptoms from a mouse bite in 2008.  After the latest occurrence, we have given lectures concerning laboratory animals and allergies. 
Furthermore, a routine serum antibody test against murine antigens has been introduced for employees working with murine animals as of November 2008.},
 title = {Case Report: Allergy and Anaphylaxis: Measures Against Laboratory Animal Allergies in NIRS},
 volume = {58},
 year = {2009}
}