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Progress and Perspectives of Carbon Ion Radiotherapy at NIRS
https://repo.qst.go.jp/records/53796
https://repo.qst.go.jp/records/53796e26d72e8-82a9-4b74-aeab-f04fda9aa118
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-01-09 | |||||
| タイトル | ||||||
| タイトル | Progress and Perspectives of Carbon Ion Radiotherapy at NIRS | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tsujii, Hirohiko
× Tsujii, Hirohiko× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In 1994, a clinical study on carbon-ion therapy was begun at NIRS using HIMAC (Heavy-Ion Medical Accelerator in Chiba), which was then the world only heavy ion accelerator complex dedicated to medical use in a hospital environment. Among several types of ion species, carbon ions were chosen for cancer therapy because they had the most optimal properties in terms of possessing, both physically and biologically, the most effective dose-localization in the body. The purpose of the clinical study was to investigate the efficacy of carbon ions against a variety of tumors as well as to develop effective techniques for delivering an efficient dose to the tumor. The RBE of carbon ions was estimated to be 2.0〜3.0 along the SOBP for acute skin reactions. As of August 2006, a total of 2,867 patients had been entered into Phase I/II or Phase II studies and analyzed for toxicity and local tumor response. The results have shown that carbon ion therapy has the potential ability to provide a sufficient dose to the tumor with acceptable morbidity in the surrounding normal tissues. Tumors that appear to respond favorably to carbon ions include locally advanced tumors and those with histologically non-squamous cell type of tumors such as adenocarcinoma, adenoid cystic carcinoma, malignant melanoma, hepatoma, and bone and soft tissue sarcoma. By taking advantage of the biological and physical properties of high-LET radiation, the efficacy of treatment regimens with small fractions in short treatment times has been confirmed for almost all types of tumors in carbon ion therapy | |||||
| 書誌情報 |
NIRS-CNAO Joint Symposium on Carbon Ion Radiotherapy 巻 NIRS-M-194, p. 27-43, 発行日 2006-11 |
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| 出版者 | ||||||
| 出版者 | National Institute of Radiological Sciences | |||||
