@inproceedings{oai:repo.qst.go.jp:00053303,
 author = {野島, 久美恵 and Ｖａｚｑｕｅｚ, Ｍａｒｃｅｌｏ Ｅ． and 長岡, 俊治 and 野島 久美恵 and 長岡 俊治},
 book = {宇宙生物科学},
 issue = {3},
 month = {Oct},
 note = {To investigate effects of low dose heavy particle radiation to CNS system, we adopted mouse neonatal brain cells in culture being exposed to heavy ions generated by HIMAC at NIRS and BNL. The applied dose varied from 0.05Gy up to 2.0Gy. The subsequent biological effects were evaluated by an induction of apoptosis focusing on the dependencies of (1) the animal strains with different radiation sensitivities, and (2) LET with different nuclei. Of the three mouse strains, SCID, B6 and C3H, used for brain cell culture, SCID was the most sensitive and C3H the least sensitive to both X-ray and carbon ions (290 MeV/n) as evaluated by 10% apoptotic criterion. However, the least sensitivity differences among the strains were much smaller in case of carbon ion comparing to that of X-ray. Regarding the LET dependency, the neon (400 MeV/n) showed 1.4 fold difference for both C3H and B6 cells. Although a LET dependency was examined by using the most sensitive SCID cells, no significant difference was detected.},
 pages = {263--264},
 title = {Effects of Low Dose Particle Radiation to Mouse Neonatal Neurons in Culture},
 volume = {17},
 year = {2004}
}