{"created":"2023-05-15T14:38:29.316474+00:00","id":52946,"links":{},"metadata":{"_buckets":{"deposit":"67e56784-e9da-440c-a57e-8b25650494c4"},"_deposit":{"created_by":1,"id":"52946","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"52946"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00052946","sets":["2"]},"author_link":["540094","540091","540095","540097","540089","540101","540093","540090","540096","540098","540092","540100","540099"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"64","bibliographicPageStart":"64","bibliographicVolumeNumber":"62","bibliographic_titles":[{"bibliographic_title":"応用物理学関係連合講演会予稿集"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　硼素中性子捕捉療法（ＢＮＣＴ）は腫瘍集積性を有する硼素薬剤と、外部から照射される熱中性子との10B(n,alpha)7Li反応から出てくるalpha, Li（飛程が細胞１個分程度）を利用して腫瘍細胞に選択的にダメージを与える放射線がん治療法で、近年研究が進められている。ＢＮＣＴでは腫瘍の細胞核に効率よく損傷を与えるための薬剤を開発する必要があり、その細胞内硼素分布の情報が必要とされている。我々はこれまで細胞内硼素文武測定を行うため、ＣＲ−３９プラスチック飛跡検出器と原子間力顕微鏡（ＡＦＭ）を用いた高分解能10B(n,alpha)7Liオートラジオフラフィの手法を開発してきた。本手法ではＣＲ−３９上に生成粒子の飛跡とともに、Ｘ線顕微鏡法を用いて細胞のＸ線透過像を転写する。Ｘ線照射前に試料に硝酸ウラニルと酢酸鉛とで染色を施すと、染料は核膜に多く集まるためその部分でＸ線の吸収量が大きく、透過型電子顕微鏡と同様の像が観察される。細胞像と粒子飛跡像とを同時に高分解能に観察できる手法である。","subitem_description_type":"Abstract"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"雨宮, 邦招"}],"nameIdentifiers":[{"nameIdentifier":"540089","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋, 浩之"}],"nameIdentifiers":[{"nameIdentifier":"540090","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中沢, 正治"}],"nameIdentifiers":[{"nameIdentifier":"540091","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中川, 義信"}],"nameIdentifiers":[{"nameIdentifier":"540092","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"清水, 秀明"}],"nameIdentifiers":[{"nameIdentifier":"540093","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"眞島, 利和"}],"nameIdentifiers":[{"nameIdentifier":"540094","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中市, 統三"}],"nameIdentifiers":[{"nameIdentifier":"540095","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安田, 仲宏"}],"nameIdentifiers":[{"nameIdentifier":"540096","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山本, 幹男"}],"nameIdentifiers":[{"nameIdentifier":"540097","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋 浩之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"540098","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中沢 正治","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"540099","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安田 仲宏","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"540100","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山本 幹男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"540101","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"CR-39とAFMを用いたBNCTマイクロドシメトリ（３）","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"CR-39とAFMを用いたBNCTマイクロドシメトリ（３）"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2002-10-28"},"publish_date":"2002-10-28","publish_status":"0","recid":"52946","relation_version_is_last":true,"title":["CR-39とAFMを用いたBNCTマイクロドシメトリ（３）"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:18:14.270257+00:00"}