@article{oai:repo.qst.go.jp:00049449,
 author = {Fujimoto, Atsushi and Hori, Yukiko and Nagai, Yuji and Kikuchi, Erika and Oyama, Kei and Suhara, Tetsuya and Minamimoto, Takafumi and Fujimoto, Atsushi and Hori, Yukiko and Nagai, Yuji and Oyama, Kei and Suhara, Tetsuya and Minamimoto, Takafumi},
 issue = {10},
 journal = {Journal of Neuroscience},
 month = {Jan},
 note = {Processing incentive and drive is essential for control of goal-directed behavior. The limbic part of the basal ganglia has been emphasized in these processes, yet the exact neuronal mechanism has remained elusive. In this study, we examined the neuronal activity of the ventral pallidum (VP) and its upstream area, the rostromedial caudate (rmCD), while two male macaque monkeys performed an instrumental lever-release task, in which a visual cue indicated the forthcoming reward size. We found that the activity of some neurons in VP and rmCD reflected the expected reward-size transiently following the cue. Reward-size coding appeared earlier and stronger in VP than in rmCD. We also found that the activity in these areas was modulated by the satiation level of monkeys, which also occurred more frequently in VP than in rmCD. The information regarding reward-size and satiation-level was independently signaled in the neuronal populations of these areas. The data thus highlighted the neuronal coding of key variables for goal-directed behavior in VP. Furthermore, pharmacological inactivation of VP induced more severe deficit of goal-directed behavior than inactivation of rmCD, which was indicated by abnormal error repetition and diminished satiation effect on the performance. These results suggest that VP encodes incentive value and internal drive, and plays a pivotal role in the control of motivation to promote goal-directed behavior.},
 pages = {1793--1804},
 title = {Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action},
 volume = {39},
 year = {2019}
}