{"created":"2023-05-15T14:38:17.035951+00:00","id":49401,"links":{},"metadata":{"_buckets":{"deposit":"5af811b9-90ee-45e0-9a27-0680dab7a9e6"},"_deposit":{"created_by":1,"id":"49401","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"49401"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00049401","sets":["1"]},"author_link":["758541","758543","758544","758542"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageStart":"1034","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Materials"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":" Physical forces are transduced into chemical reactions, thereby ultimately making a large impact on the whole-animal level phenotypes such as homeostasis, development and behavior. To understand mechano-chemical transduction, mechanical input should be quantitatively delivered with controllable vibration properties–frequency, amplitude and duration, and its chemical output should be noninvasively quantified in an unconstrained animal. However, such an experimental system has not been established so far. Here, we develop a noninvasive and unconstrained mechanochemical imaging microscopy. This microscopy enables us to evoke nano-scale nonlocalized vibrations with controllable vibration properties using a piezoelectric acoustic transducer system and quantify calcium response of a freely moving C. elegans at a single cell resolution. Using this microscopy, we clearly detected the calcium response of a single interneuron during C. elegans escape response to nano-scale vibration. Thus, this microscopy will facilitate understanding in vivo mechanochemical physiology in the future.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/ma11061034","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.mdpi.com/1996-1944/11/6/1034","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1996-1944","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sugi, Takuma"}],"nameIdentifiers":[{"nameIdentifier":"758541","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Igarashi, Ryuji"}],"nameIdentifiers":[{"nameIdentifier":"758542","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishimura , Masaki"}],"nameIdentifiers":[{"nameIdentifier":"758543","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Igarashi, Ryuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"758544","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Noninvasive mechanochemical imaging in unconstrained Caenorhabditis elegans","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Noninvasive mechanochemical imaging in unconstrained Caenorhabditis elegans"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-13"},"publish_date":"2018-06-13","publish_status":"0","recid":"49401","relation_version_is_last":true,"title":["Noninvasive mechanochemical imaging in unconstrained Caenorhabditis elegans"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:45:44.848907+00:00"}