{"created":"2023-05-15T14:38:15.938400+00:00","id":49383,"links":{},"metadata":{"_buckets":{"deposit":"e5a2a168-90eb-4b27-a3f3-907995ff5856"},"_deposit":{"created_by":1,"id":"49383","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"49383"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00049383","sets":["1"]},"author_link":["788659","788667","788669","788657","788668","788656","788665","788655","788662","788658","788661","788671","788664","788663","788670","788666","788660"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"6083","bibliographicPageStart":"6077","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Cancer medicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND: \nThis multi-institutional retrospective study focused on the clinical outcome of carbon-ion radiotherapy (C-ion RT) for non-squamous cell malignant tumors of the nasopharynx.\nMETHODS: \nThe Japan Carbon-ion Radiation Oncology Study Group collected and analyzed data for 43 patients with non-squamous cell malignant tumors of the nasopharynx treated with C-ion RT at four institutions in Japan.\nRESULTS: \nTwenty-nine patients had adenoid cystic carcinomas, seven had malignant melanomas, three had adenocarcinomas, two had mucoepidermoid carcinomas, and two had other pathologies. Twenty-six of the 43 patients (61%) had T4 tumors. The most common dose-fractionation schedule was 64 Gy (relative biological effectiveness) in 16 fractions. The median follow-up period was 30 months. The 2-year local control (LC) and overall survival (OS) rates were 88% and 84%, respectively. For late toxicity, one patient developed grade 4 optic nerve disorder and two developed grade 5 pharyngeal hemorrhage. Actual incidence of grade 3 or higher late adverse events was 19%, and included cranial nerve dysfunction, jaw bone necrosis, central nervous system necrosis, and ear inflammation.\nCONCLUSIONS: \nC-ion RT provided good LC and OS rates with acceptable toxicity for treatment of non-squamous cell malignant tumors of the nasopharynx.\n","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"30449067","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1002/cam4.1884","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.1884","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2045-7634","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abe, Takanori"}],"nameIdentifiers":[{"nameIdentifier":"788655","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohno, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"788656","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"788657","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Demizu, Yusuke"}],"nameIdentifiers":[{"nameIdentifier":"788658","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suefuji, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"788659","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"788660","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okimoto, Tomoaki"}],"nameIdentifiers":[{"nameIdentifier":"788661","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shioyama, Yoshiyuki"}],"nameIdentifiers":[{"nameIdentifier":"788662","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jun-Ichi, Saitoh"}],"nameIdentifiers":[{"nameIdentifier":"788663","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shirai, Katsuyuki"}],"nameIdentifiers":[{"nameIdentifier":"788664","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nemoto, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"788665","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakano, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"788666","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"788667","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Japan, Carbon‐Ion Radiation Oncology Study Group"}],"nameIdentifiers":[{"nameIdentifier":"788668","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"788669","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"788670","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"788671","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A multi-institutional retrospective study of carbon-ion radiotherapy for non-squamous cell malignant tumors of the nasopharynx: Subanalysis of Japan Carbon-Ion Radiation Oncology Study Group study 1402 HN.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A multi-institutional retrospective study of carbon-ion radiotherapy for non-squamous cell malignant tumors of the nasopharynx: Subanalysis of Japan Carbon-Ion Radiation Oncology Study Group study 1402 HN."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-12-28"},"publish_date":"2018-12-28","publish_status":"0","recid":"49383","relation_version_is_last":true,"title":["A multi-institutional retrospective study of carbon-ion radiotherapy for non-squamous cell malignant tumors of the nasopharynx: Subanalysis of Japan Carbon-Ion Radiation Oncology Study Group study 1402 HN."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:05:44.035601+00:00"}