@article{oai:repo.qst.go.jp:00049354, author = {Isozaki, Yuka and Yasuda, Shigeo and Akutsu , Yasunori and Shimada , Hideaki and Okazumi, Shinichi and Nabeya, Yoshihiro and Hoshino , Isamu and Murakami , Kentaro and Ebner, Daniel and Tsuji, Hiroshi and Kamada, Tadashi and Yamada, Shigeru and H, Matsubara and Isozaki, Yuka and Yasuda, Shigeo and Ebner, Daniel and Tsuji, Hiroshi and Kamada, Tadashi and Yamada, Shigeru}, issue = {11}, journal = {Anticancer Research}, month = {Oct}, note = {AIM: Evaluation of the therapeutic efficacy of carbon-ion radiation therapy for isolated lymph node recurrence following curative resection of esophageal cancer. MATERIALS AND METHODS: Ten cases with lymph node recurrence after esophageal cancer surgery were treated with carbon-ion radiation therapy. A total of 48.0 Gy [relative biologic effectiveness (RBE)] was delivered over 3 weeks with a daily dose of 4.0 Gy (RBE). RESULTS: The median follow-up duration was 27.1 months (range=3-92.0 months) after carbon-ion radiation therapy. The local control rates at 2, 3 and 5 years were 92.4%. The overall survival rates at 2, 3 and 5 years were 70.0%, 58.3% and 21.9%. The median survival period was 45.3 months after carbon-ion radiation therapy. There were no toxicities of grade 3 or higher. CONCLUSION: Carbon-ion radiation therapy may be a safe and effective treatment option for isolated lymph node recurrence after radical surgery for esophageal cancer.}, pages = {6453--6458}, title = {Salvage Carbon-ion Radiotherapy for Isolated Lymph Node Recurrence Following Curative Resection of Esophageal Cancer.}, volume = {38}, year = {2018} }