@article{oai:repo.qst.go.jp:00048973, author = {Lachlan, Chartier and Thuy Linh, Tran and David, BOLST and Guatelli, Susanna and Pogossov, A. and Anthony, Prokopovich and I. Reinhard, M. and Perevertaylo, V. and Anderson, S. and Beltran, C. and 松藤, 成弘 and Jackson, M. and Rozenfeld, Anatoly and Lachlan, Chartier and Linh Tran, Thuy and BOLST, David and Prokopovich, Anthony and Matsufuji, Naruhiro and Anatoly, Rozenfeld}, issue = {1-4}, journal = {Radiation Protection Dosimetry}, month = {Oct}, note = {Using the CMRP ‘bridge' μ+ probe, microdosimetric measurements were undertaken out-of-field using a therapeutic scanning proton pencil beam and in-field using a 12C ion therapy field. These measurements were undertaken at Mayo Clinic, Rochester, USA and at HIMAC, Chiba, Japan, respectively. For a typical proton field used in the treatment of deep-seated tumors, we observed dose-equivalent values ranging from 0.62 to 0.99 mSv/Gy at locations downstream of the distal edge. Lateral measurements at depths close to the entrance and along the SOBP plateau were found to reach maximum values of 3.1 mSv/Gy and 5.3 mSv/Gy at 10 mm from the field edge, respectively, and decreased to ~0.04 mSv/Gy 120 mm from the field edge. The ability to measure the dose-equivalent with high spatial resolution is particularly relevant to healthy tissue dose calculations in hadron therapy treatments. We have also shown qualitatively and quantitively the effects critical organ motion would have in treatment using microdosimetric spectra. Large differences in spectra and RBE10 were observed for treatments where miscalculations of 12C ion range would result in critical structures being irradiated, showing the importance of motion management.}, pages = {365--371}, title = {MICRODOSIMETRIC APPLICATIONS IN PROTON AND HEAVY ION THERAPY USING SILICON MICRODOSIMETERS}, volume = {180}, year = {2017} }