@article{oai:repo.qst.go.jp:00048830,
 author = {Hazawa, Masaharu and Yasuda, Takeshi and Noshiro, Katsuko and Saotome, Ai and Fukuzaki, Tomoko and Michikawa, Yuichi and Gotoh, Takaya and Tajima, Katsushi and 羽澤 勝治 and 安田 武嗣 and 野代 勝子 and 早乙女 愛 and 福崎 智子 and 道川 祐市 and 後藤 孝也 and 田嶋 克史},
 journal = {FEBS Open Bio (Online Only URL:http://www.sciencedirect.com/science/journal/22115463)},
 month = {Oct},
 note = {Vitronectin (VN) is a multi-functional protein involved in extracellular matrix (ECM)-cell binding through integrin receptors on the cell surface, which is an important environmental process for maintaining biological homeostasis. We investigated how VN affects the survival of endothelial cells after radiation damage. VN attenuated radiation-induced expression of p21, an inhibitor of cell cycle progression, and selectively inhibited Erk- and p38 MAPK-dependent p21 induction after radiation exposure through regulation of the activity of GSK-3b. VN also reduced the cleavage of caspase-3, thereby inhibiting radiation-induced apoptotic cell death. These results suggest that VN has important roles in cell survival after radiation damage.},
 pages = {334--338},
 title = {Vitronection improves cell survival after radiation injury in human umbilical vein endothelial cells.},
 volume = {2},
 year = {2012}
}