{"created":"2023-05-15T14:37:40.925232+00:00","id":48608,"links":{},"metadata":{"_buckets":{"deposit":"e9229fec-1d2b-494e-b150-a9952eefb890"},"_deposit":{"created_by":1,"id":"48608","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48608"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048608","sets":["1"]},"author_link":["488767","488768","488770","488771","488775","488769","488772","488773","488774","488776","488778","488777"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"46","bibliographicPageStart":"40","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Journal of Clinical Biochemistry and Nutrition"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Temperature-dependent free radical reactions were investigated using nitroxyl radicals as redox probes. Reactions of two types of nitroxyl radicals, TEMPOL (4-hydroxyl-2,2,6,6-tetramethylpiperidine-N-oxyl) and carbamoyl-PROXYL (3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl), were tested in this paper. Heating a solution containing a nitroxyl radical and a reduced form of glutathione (GSH) caused temperature-dependent decay of electron paramagnetic resonance (EPR) signal intensity of the nitroxyl radical. Heating a solution of the corresponding hydroxylamine form of the nitroxyl radical showed EPR signal recovery. The GSH-dependent reduction of nitroxyl radicals at 70[Deg]C was suppressed by antioxidants, spin trapping agents, and/or bubbling N2 gas, although heating carbamoyl-PROXYL with GSH showed temporarily enhanced signal decay by bubbling N2 gas. Since SOD could restrict the GSH-dependent EPR signal decay of TEMPOL, O2- is related with this reaction. O2- was probably generated from dissolved oxygen in the reaction mixture. Oxidation of the hydroxylamines at 70[Deg]C was also suppressed by bubbling N2 gas. Heating a solution of spin trapping agent, DMPO (5,5-dimethyl-1-pyrroline-N-oxide) showed a temperature-dependent increase of the EPR signal of the hydroxyl radical adduct of DMPO. Synthesis of hydroxyl radical adduct of DMPO at 70[Deg]C was suppressed by antioxidants and/or bubbling N2 gas. The results suggested that heating an aqueous solution containing oxygen can generate reactive oxygen species, mainly O2-.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3164/jcbn.10-145","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.jstage.jst.go.jp/article/jcbn/50/1/50_10-145/_article"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/article/jcbn/50/1/50_10-145/_article","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0912-0009","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsumoto, Ken-ichiro"}],"nameIdentifiers":[{"nameIdentifier":"488767","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nyuui, Minako"}],"nameIdentifiers":[{"nameIdentifier":"488768","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamibayashi, Masato"}],"nameIdentifiers":[{"nameIdentifier":"488769","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ozawa, Toshihiko"}],"nameIdentifiers":[{"nameIdentifier":"488770","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakanishi, Ikuo"}],"nameIdentifiers":[{"nameIdentifier":"488771","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Anzai, Kazunori"}],"nameIdentifiers":[{"nameIdentifier":"488772","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本 謙一郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488773","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"乳井 美奈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488774","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上林 將人","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488775","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小澤 俊彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488776","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中西 郁夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488777","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安西 和紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488778","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Temperature-Dependent Free Radical Reaction in Water","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Temperature-Dependent Free Radical Reaction in Water"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-03-22"},"publish_date":"2018-03-22","publish_status":"0","recid":"48608","relation_version_is_last":true,"title":["Temperature-Dependent Free Radical Reaction in Water"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:26:16.644766+00:00"}