@article{oai:repo.qst.go.jp:00048599,
 author = {Matsumoto, Ken-ichiro and Narazaki, Michiko and Ikehira, Hiroo and Anzai, Kazunori and Ikota, Nobuo and 松本 謙一郎 and 楢崎 美智子 and 池平 博夫 and 安西 和紀 and 伊古田 暢夫},
 issue = {1},
 journal = {Journal of Magnetic Resonance},
 month = {Jun},
 note = {The resolution and signal to noise ratio of EPR imaging and T1-weighted MRI were compared using an identical phantom. Several solutions of nitroxyl contrast agents with different EPR spectral shapes were tested. The feasibility of T1-weighted MRI to detect nitroxyl contrast agents was described. T1-weighted MRI can detect nitroxyl contrast agents with a complicated EPR spectrum easier and quicker; however, T1-weighted MRI has less quantitative ability especially for lipophilic nitroxyl contrast agents, because T1-relaxivity, i.e. accessibility to water, is affected by the hydrophilic/hydrophobic micro-environment of a nitroxyl contrast agent. The less quantitative ability of T1-weighted MRI may not be a disadvantage of redox imaging, which obtains reduction rate of a nitroxyl contrast. Therefore, T1-weighted MRI has a great advantage to check the pharmacokinetics of newly modified and/or designed nitroxyl contrast agents. 2007 Elsevier Inc. All rights reserved.},
 pages = {155--162},
 title = {Comparisons of EPR imaging and T(1)-weighted MRI for efficient imaging of nitroxyl contrast agents.},
 volume = {187},
 year = {2007}
}