{"created":"2023-05-15T14:37:37.872498+00:00","id":48549,"links":{},"metadata":{"_buckets":{"deposit":"e04aa650-3b99-4625-8268-015c2d43044a"},"_deposit":{"created_by":1,"id":"48549","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48549"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048549","sets":["1"]},"author_link":["488109","488100","488103","488098","488105","488111","488104","488107","488110","488099","488106","488102","488101","488108"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-04","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"60","bibliographicPageStart":"56","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Nuclear Medicine and Biology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: Copper-67 is an attractive beta emitter for targeted radionuclide therapy. However, the availability of 67Cu limits its potential use in a wide range of applications. In this study, we propose an easy small-scale production of 67Cu using 64Ni target for a preclinical study. \nMethods: 67Cu was produced from an electrodeposited 64Ni target via the 64Ni(α, p)67Cu-reaction with a 36 MeV alpha beam at 15 eμA (electrical microampere) conducted for 7 h. The chemical separation process of 67Cu from the 64Ni target was performed following by our routine procedure of 64Cu production using cation exchange resin, AG50W-X8, with minor modification. The target and its holder were redesigned in the preparation.\nResults: The 67Cu product was obtained with a yield of 55 ± 10 MBq at the end of bombardment (EOB), and the yield was 527 ± 96 kBq/μAh at the EOB. The copper impurity in the product was low (0.71 ± 0.21 μg) and the product was suitable for a preclinical study.\nConclusions: We produced 67Cu with sufficient activity and quality for a preclinical study using a 64Ni-target. This production method also showed advantages as a routine method, i.e., shorten the processing time, reducing the radiation exposure and ready target recycling, when compared with that of a conventional Zn-target used for 67Cu production.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.nucmedbio.2018.01.002","subitem_relation_type_select":"DOI"}}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohya, Tomoyuki"}],"nameIdentifiers":[{"nameIdentifier":"488098","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhang, Ming-Rong"}],"nameIdentifiers":[{"nameIdentifier":"488099","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagatsu, Kotaro"}],"nameIdentifiers":[{"nameIdentifier":"488100","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukada, Masami"}],"nameIdentifiers":[{"nameIdentifier":"488101","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hanyu, Masayuki"}],"nameIdentifiers":[{"nameIdentifier":"488102","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Hisashi"}],"nameIdentifiers":[{"nameIdentifier":"488103","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Minegishi, Katsuyuki"}],"nameIdentifiers":[{"nameIdentifier":"488104","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大矢 智幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488105","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 明栄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488106","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永津 弘太郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488107","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"深田 正美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488108","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"破入 正行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488109","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 寿","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488110","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"峯岸 克行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"488111","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":" Small-scale production of 67Cu for a preclinical study via the 64Ni(α, p)67Cu channel","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":" Small-scale production of 67Cu for a preclinical study via the 64Ni(α, p)67Cu channel"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-02-28"},"publish_date":"2018-02-28","publish_status":"0","recid":"48549","relation_version_is_last":true,"title":[" Small-scale production of 67Cu for a preclinical study via the 64Ni(α, p)67Cu channel"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:26:54.944264+00:00"}