{"created":"2023-05-15T14:37:37.530134+00:00","id":48541,"links":{},"metadata":{"_buckets":{"deposit":"08d9dc84-f570-43c7-bc72-a216c9673717"},"_deposit":{"created_by":1,"id":"48541","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48541"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048541","sets":["1"]},"author_link":["796031","796030","796025","796035","796026","796029","796033","796036","796028","796034","796037","796024","796027","796032"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-11","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":" Journal of Nuclear Cardiology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND:\n11C-hydroxyephedrine (HED) PET has been used to evaluate the myocardial sympathetic nervous system (SNS). Here we sought to establish a simultaneous approach for quantifying both myocardial blood flow (MBF) and the SNS from a single HED PET scan.\nMETHODS:\nTen controls and 13 patients with suspected cardiac disease were enrolled. The inflow rate of 11C-HED (K1) was obtained using a one-tissue-compartment model. We compared this rate with the MBF derived from 15O-H2O PET. In the controls, the relationship between K 1 from 11C-HED PET and the MBF from 15O-H2O PET was linked by the Renkin-Crone model.\nRESULTS:\nThe relationship between K 1 from 11C-HED PET and the MBF from 15O-H2O PET from the controls' data was approximated as follows: K 1  =  (1 - 0.891 * exp(- 0.146/MBF)) * MBF. In the validation set, the correlation coefficient demonstrated a significantly high relationship for both the whole left ventricle (r = 0.95, P < 0.001) and three coronary territories (left anterior descending artery: r = 0.96, left circumflex artery: r = 0.81, right coronary artery: r =  0.86; P < 0.001, respectively).\nCONCLUSION:\n11C-HED can simultaneously estimate MBF and sympathetic nervous function without requiring an additional MBF scan for assessing mismatch areas between MBF and SNS.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"29270771","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12350-017-1140-4","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://link.springer.com/article/10.1007/s12350-017-1140-4","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1532-6551","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hiroshima, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"796024","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Manabe, Osamu"}],"nameIdentifiers":[{"nameIdentifier":"796025","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naya, Masanao"}],"nameIdentifiers":[{"nameIdentifier":"796026","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomiyama, Yuuki"}],"nameIdentifiers":[{"nameIdentifier":"796027","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Magota, Keiichi"}],"nameIdentifiers":[{"nameIdentifier":"796028","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Obara, Masahiko"}],"nameIdentifiers":[{"nameIdentifier":"796029","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aikawa, Tadao"}],"nameIdentifiers":[{"nameIdentifier":"796030","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noriko, Oyama-Manabe"}],"nameIdentifiers":[{"nameIdentifier":"796031","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshinaga, Keiichiro"}],"nameIdentifiers":[{"nameIdentifier":"796032","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirata, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"796033","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kroenke, Markus"}],"nameIdentifiers":[{"nameIdentifier":"796034","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tamaki, Nagara"}],"nameIdentifiers":[{"nameIdentifier":"796035","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katoh, Chietsugu"}],"nameIdentifiers":[{"nameIdentifier":"796036","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshinaga, Keiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"796037","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Quantification of myocardial blood flow with 11C-hydroxyephedrine dynamic PET: comparison with 15O-H2O PET.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Quantification of myocardial blood flow with 11C-hydroxyephedrine dynamic PET: comparison with 15O-H2O PET."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-27"},"publish_date":"2017-12-27","publish_status":"0","recid":"48541","relation_version_is_last":true,"title":["Quantification of myocardial blood flow with 11C-hydroxyephedrine dynamic PET: comparison with 15O-H2O PET."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:55:06.872017+00:00"}