@article{oai:repo.qst.go.jp:00048530,
 author = {Sekine, Emiko and Nakanishi, Ikuo and Shimokawa, Takashi and Ueno, Megumi and Matsumoto, Ken-ichiro and Murakami, Takeshi and 関根 絵美子 and 中西 郁夫 and 下川 卓志 and 上野 恵美 and 松本 謙一郎 and 村上 健},
 issue = {16},
 journal = {Analytical Chemistry},
 month = {Aug},
 note = {We invented a high-throughput screening method for the examination of radioprotective activity of chemical compounds using rat thymocytes. X-irradiation of the rat thymocytes induced apoptosis, leading to a significant cell shrinkage, which could be easily detected and directly quantified by the flow cytometry analysis. The protective effect of some natural antioxidants against radiation induced apoptosis in the rat thymocytes, as well as their toxicities without X-irradiation, was successfully evaluated using this method. This method provides a powerful tool to develop novel radioprotectors without toxicity and can also be widely used to estimate other oxidative stress except for radiation.},
 pages = {7650--7653},
 title = {High-Throughput Screening of Radioprotectors Using Rat Thymocytes},
 volume = {85},
 year = {2013}
}