@article{oai:repo.qst.go.jp:00048491,
 author = {Hama, Yukihiro and Matsumoto, Ken-ichiro and Murugesan, Ramachandran and Subramanian, Sankaran and Devasahayam, Nallathamby and W., Koscielniak Janusz and Hyodo, Fuminori and A., Cook John and B., Mitchell James and C., Krishna Murali and 松本 謙一郎},
 issue = {10},
 journal = {Antioxidants & Redox Signaling},
 month = {Oct},
 note = {A novel continuous wave (CW), radiofrequency (RF), electron paramagnetic resonance (EPR) oximetric imaging technique is proposed, based on the influence of oxygen concentration on the RF power saturation of the EPR resonance. A linear relationship is demonstrated between the partial oxygen pressure (pO2) and the normalized signal intensity (IN), defined as, IN = (IHP - ILP) / ILP, where ILP and IHP refer to signal intensities at low (PL) and high (PH) RF power levels, respectively. A formula for the determination of pO2, derived on the basis of the experimental results, reliably estimated various oxygen concentrations in a five-tube phantom. This new technique was time-efficient and also avoided the missing angle problem associated with conventional spectral-spatial CW EPR oximetric imaging. In vivo power saturation oximetric imaging in a tumor bearing mouse clearly depicted the hypoxic foci within the tumor.},
 pages = {1709--1716},
 title = {Continuous wave EPR oximetric imaging at 300 MHz using radiofrequency power saturation effects},
 volume = {9},
 year = {2007}
}