@article{oai:repo.qst.go.jp:00048455,
 author = {Furusawa, Yoshiya and Nakano-Aoki, Mizuho and Matsumoto, Yoshitaka and Hirayama, Ryoichi and Kobayashi, Alisa and Konishi, Teruaki and 古澤 佳也 and 青木 瑞穂 and 松本 孔貴 and 平山 亮一 and 小林 亜利紗 and 小西 輝昭},
 issue = {6},
 journal = {Journal of Radiation Research},
 month = {Jun},
 note = {To make the quality of the sublethal damage (SLD) after high-linear energy transfer (LET) ion beams was investigated with low-LET photons. Chinese hamster V79 cells and human squamous carcinoma SAS cells were first exposed to a priming dose of different ion beams at different LETs at the Heavy Ion Medical Accelerator in Chiba facility. The cells were kept at room temperature and then exposed to a secondary test dose of X-rays. Based on the repair kinetics study, the surviving fraction of cells quickly increased with the repair time, and reached a plateau in 2-3 h, even when cells had received priming monoenergetic high-LET beams or spread-out Bragg peak beams as well as X-ray. The shapes of the cell survival curves from the secondary test X-ray, after repair of the damage caused by the high-LET radiations, were similar to those obtained from cells exposed to primary X-ray only. Complete SLD repairs were observed even when the LET of the primary ion beams was very high. These results suggest that the SLD caused by high-LET radiations was repaired well, and likewise the damage caused by the X-ray. In cells where the ion beam had made a direct hit to the core region in an ion track, lethal damage to the domain was produced, resulting in cell death. On the other hand, in domains that had received a glancing hit at the low-LET penumbra region, the SLD produced was completely repaired.},
 pages = {803--808},
 title = {Equivalency of the Quality of Sub-lethal Lesions after Photons and High-Linear Energy Transfer Ion Beams},
 volume = {58},
 year = {2017}
}