@article{oai:repo.qst.go.jp:00048392,
 author = {Wang, Lu and Cheng, Ran and Fujinaga, Masayuki and Yang, Jian and Zhang, Yiding and Hatori, Akiko and Kumata, Katsushi and Yang, Jing and Vasdev, Neil and Du, Yunfei and Ran, Chongzhao and Zhang, Ming-Rong and Steven, H. Liang and 藤永 雅之 and 張 一鼎 and 羽鳥 晶子 and 熊田 勝志 and 張 明栄},
 issue = {12},
 journal = {Journal of Medicinal Chemistry},
 month = {May},
 note = {A suitable TSPO PET ligand may visualize and quantify neuroinflammation in a living brain. Herein we report a 18F-ligand, [18F]2 ([18F]FDPA), is radiolabeled in high yield and high specific activity based on our spirocyclic iodonium ylide (SCIDY) strategy. [18F]2 demonstrated saturable specific binding to TSPO, substantially elevated brain uptake, and slow washout of bound PET signal in the preclinical models of brain neuroinflammation (cerebral ischemia and Alzheimer's disease).},
 pages = {5222--5227},
 title = {A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation.},
 volume = {60},
 year = {2017}
}