{"created":"2023-05-15T14:37:30.669268+00:00","id":48384,"links":{},"metadata":{"_buckets":{"deposit":"2c61e9df-efa9-4ec4-9fb6-efdd3abbd90a"},"_deposit":{"created_by":1,"id":"48384","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48384"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048384","sets":["1"]},"author_link":["486308","486307","486312","486309","486310","486311","486314","486313"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"892","bibliographicPageStart":"889","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"Experimental Dermatology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Radiation-induced hair loss is a clinically important, but under-researched topic. The aim of study was to develop an in vivo assay system for radiation-induced apoptosis in hair follicles to promote hair research and exploit new radioprotectors. BALB/c mice received total body irradiation (TBI) with gamma-rays at doses in the range from 8 to 16 Gy at 6 days after depilation. Pathological changes were detected progressively in the hair follicles over the time course after TBI and the dystrophy was evaluated on the basis of stage-specific parameters reported previously, which were found to be well-suited for classification of the radiation-induced hair follicle dystrophy. As a result, regression from anagen to catagen was determined in these follicles after irradiation. In addition, radiation-induced apoptosis was a good early dystrophic parameter. In this system, it was found that fibroblast growth factor-1 effectively prevented hair follicle apoptosis in mice.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0906-6705","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakayama, Fumiaki"}],"nameIdentifiers":[{"nameIdentifier":"486307","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hagiwara, Akiko"}],"nameIdentifiers":[{"nameIdentifier":"486308","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Miho"}],"nameIdentifiers":[{"nameIdentifier":"486309","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akashi, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"486310","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imamura, Toru"}],"nameIdentifiers":[{"nameIdentifier":"486311","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中山 文明","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"486312","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"萩原 亜紀子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"486313","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"明石 真言","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"486314","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of radiation-induced hair follicle apoptosis in mice and the preventive effects of fibroblast growth factor-1","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of radiation-induced hair follicle apoptosis in mice and the preventive effects of fibroblast growth factor-1"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-11-22"},"publish_date":"2017-11-22","publish_status":"0","recid":"48384","relation_version_is_last":true,"title":["Evaluation of radiation-induced hair follicle apoptosis in mice and the preventive effects of fibroblast growth factor-1"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:28:43.969445+00:00"}