{"created":"2023-05-15T14:37:23.020422+00:00","id":48209,"links":{},"metadata":{"_buckets":{"deposit":"f3a5b6e2-ebfe-438b-86e7-7c5649d7b48d"},"_deposit":{"created_by":1,"id":"48209","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48209"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048209","sets":["1"]},"author_link":["484315","484322","484320","484319","484323","484321","484326","484318","484325","484316","484317","484324"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"4606","bibliographicPageStart":"4601","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Anticancer Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Nano-scale drug delivery systems (nano-DDS) are under active investigation. Nano-platforms are developed for specific administration of small molecules, drugs, genes, contrast agents [quantum dots (QDs] both in vivo and in vitro. Electroporation is a biophysical phenomenon which consists of the application of external electrical pulses across the cell membrane. The aim of this study was to research electro-assisted Colon 26 cell line internalization of QDs and QD-loaded nano-hydrogels (polymersomes) visualized by confocal microscopy and their influence on cell viability. Materials and Methods: The experiments were performed on the Colon 26 cancer cell line, using a confocal fluorescent imaging system and cell viability test. Results: Electroporation facilitated the delivery of nanoparticles in vivo. We demonstrated increased voltagedependent delivery of nanoparticles into cells after electrotreatment, without significant cell viability reduction. Conclusion: The delivery and retention of the polymersomes in vitro is a promising tool for future cancer treatment strategies and nanomedcine.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"International Institute of Anticancer Research (IIAR)"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.21873/anticanres.11009","subitem_relation_type_select":"DOI"}}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Atanasova, Severina"}],"nameIdentifiers":[{"nameIdentifier":"484315","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nikolova, Biliana"}],"nameIdentifiers":[{"nameIdentifier":"484316","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Murayama, Shuhei"}],"nameIdentifiers":[{"nameIdentifier":"484317","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Stoyanova, Elena"}],"nameIdentifiers":[{"nameIdentifier":"484318","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsoneva, Iana"}],"nameIdentifiers":[{"nameIdentifier":"484319","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhelev, Zhivko"}],"nameIdentifiers":[{"nameIdentifier":"484320","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoki, Ichio"}],"nameIdentifiers":[{"nameIdentifier":"484321","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Bakalova, Rumiana"}],"nameIdentifiers":[{"nameIdentifier":"484322","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村山 周平","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"484323","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｚｈｅｌｅｖ Ｚｈｉｖｋｏ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"484324","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青木 伊知男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"484325","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"バカロバ ルミアナ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"484326","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Electroinduced Delivery of Hydrogel Nanoparticles in Colon 26 Cells, Visualized by Confocal Fluorescence System","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Electroinduced Delivery of Hydrogel Nanoparticles in Colon 26 Cells, Visualized by Confocal Fluorescence System"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-07-26"},"publish_date":"2017-07-26","publish_status":"0","recid":"48209","relation_version_is_last":true,"title":["Electroinduced Delivery of Hydrogel Nanoparticles in Colon 26 Cells, Visualized by Confocal Fluorescence System"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:30:41.689231+00:00"}