{"created":"2023-05-15T14:37:21.034462+00:00","id":48164,"links":{},"metadata":{"_buckets":{"deposit":"6b50fac1-b2c0-44b6-aea3-22a9252a0f8c"},"_deposit":{"created_by":1,"id":"48164","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48164"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048164","sets":["1"]},"author_link":["483757","483759","483749","483758","483756","483763","483750","483753","483760","483755","483762","483752","483761","483751","483754"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-02","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"45","bibliographicPageStart":"41","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"Clinical and Translational Radiation Oncology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and purpose: The efficacy of carbon ion radiotherapy (CIRT) for bone and soft tissue sarcoma\nhas been reported recently. Although histological assessment after CIRT requires skilled interpretation,\nlittle information is presently available. In this study, we report sequential histological findings after\ntreatment with CIRT, and evaluate the association between these findings and clinical response.\nMaterial and methods: Seven patients with unresectable sarcoma underwent needle biopsy 12 times at an\naverage of 14.3 months after CIRT and were included in this study.\nResults: One patient underwent two biopsies after CIRT for chordoma. Although a few suspected residual\nchordoma cells were observed at 19 and 30 months after CIRT, the tumor continued to shrink at 75 months.\nImmunohistochemical analysis of post-CIRT specimens revealed CK AE1/3, EMA, and S100 expression, as in\nthe pre-CIRT specimen. In total, viable tumor cells were found in 9 of 12 specimens; however, only 2\npatients showed recurrent masses on radiological examination. The other 5 patients had stable disease.\nConclusions: Viable tumor cells after CIRT did not always cause recurrence. This may be due to observation\nof dying cells or radiation-induced deformed cells. Histological evaluation after CIRT should be done\ncarefully.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"ELSEVIER"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ctro.2017.01.002","subitem_relation_type_select":"DOI"}}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Katsuhiro"}],"nameIdentifiers":[{"nameIdentifier":"483749","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Norio"}],"nameIdentifiers":[{"nameIdentifier":"483750","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shirai, Toshiharu"}],"nameIdentifiers":[{"nameIdentifier":"483751","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akihiko, Takeuchi"}],"nameIdentifiers":[{"nameIdentifier":"483752","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"483753","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miwa, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"483754","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Higuchi, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"483755","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Abe, Kensaku"}],"nameIdentifiers":[{"nameIdentifier":"483756","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yuta, Taniguchi"}],"nameIdentifiers":[{"nameIdentifier":"483757","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aiba, Hisaki"}],"nameIdentifiers":[{"nameIdentifier":"483758","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kiyohara, Hiroki"}],"nameIdentifiers":[{"nameIdentifier":"483759","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imai, Reiko"}],"nameIdentifiers":[{"nameIdentifier":"483760","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikeda, Hiroko"}],"nameIdentifiers":[{"nameIdentifier":"483761","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroyuki, Tsuchiya"}],"nameIdentifiers":[{"nameIdentifier":"483762","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 礼子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"483763","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Sequential histological findings and clinical response after carbon ion radiotherapy for unresectable sarcoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Sequential histological findings and clinical response after carbon ion radiotherapy for unresectable sarcoma"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-07-24"},"publish_date":"2017-07-24","publish_status":"0","recid":"48164","relation_version_is_last":true,"title":["Sequential histological findings and clinical response after carbon ion radiotherapy for unresectable sarcoma"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:31:12.230691+00:00"}