{"created":"2023-05-15T14:37:19.989378+00:00","id":48140,"links":{},"metadata":{"_buckets":{"deposit":"4d118d85-09aa-4f06-bce2-dc991fb474fe"},"_deposit":{"created_by":1,"id":"48140","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"48140"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00048140","sets":["1"]},"author_link":["483404","483402","483406","483405","483407","483403"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"15","bibliographicPageEnd":"5836","bibliographicPageStart":"5818","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"Physics in Medicine & Biology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A simple and efficient approach is needed for robustness evaluation and\noptimization of treatment planning in routine clinical particle therapy. Here\nwe propose a robustness analysis method using dose standard deviation (SD)\nin possible scenarios such as the robustness indicator and a fast dose warping\nmethod, i.e. deformation of dose distributions, taking into account the setup\nand range errors in carbon-ion therapy. The dose warping method is based on\nthe nominal dose distribution and the water-equivalent path length obtained\nfrom planning computed tomography data with a clinically commissioned\ntreatment planning system (TPS). We compared, in a limited number\nof scenarios at the extreme boundaries of the assumed error, the dose SD\ndistributions obtained by the warping method with those obtained using the\nTPS dose recalculations. The accuracy of the warping method was examined\nby the standard-deviation-volume histograms (SDVHs) for varying degrees\nof setup and range errors for three different tumor sites. Furthermore, the\ninfluence of dose fractionation on the combined dose uncertainty, taking into\nconsideration the correlation of setup and range errors between fractions, was\nevaluated with simple equations using the SDVHs and the mean value of SDs in\nthe defined volume of interest. The results of the proposed method agreed well\nwith those obtained with the dose recalculations in these comparisons, and the\neffectiveness of dose SD evaluations at the extreme boundaries of given errors\nwas confirmed from the responsivity and DVH analysis of relative SD values\nfor each error. The combined dose uncertainties depended heavily on the\nnumber of fractions, assumed errors and tumor sites. The typical computation\ntime of the warping method is approximately 60 times less than that of the full dose calculation method using the TPS. The dose SD distributions and\nSDVHs with the fractionation effect will be useful indicators for robustness\nanalysis in treatment planning, and the results of our comparative study show\nthat the proposed analysis method would be beneficial in routine clinical use.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"IOP Publishing"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"27426737","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1088/0031-9155/61/15/5818","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0031-9155","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakama, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"483402","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanematsu, Nobuyuki"}],"nameIdentifiers":[{"nameIdentifier":"483403","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inaniwa, Taku"}],"nameIdentifiers":[{"nameIdentifier":"483404","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂間 誠","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"483405","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"兼松 伸幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"483406","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"稲庭 拓","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"483407","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A robustness analysis method with fast estimation of dose uncertainty distributions for carbon-ion therapy treatment planning","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A robustness analysis method with fast estimation of dose uncertainty distributions for carbon-ion therapy treatment planning"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-07-24"},"publish_date":"2017-07-24","publish_status":"0","recid":"48140","relation_version_is_last":true,"title":["A robustness analysis method with fast estimation of dose uncertainty distributions for carbon-ion therapy treatment planning"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:31:29.582660+00:00"}