@article{oai:repo.qst.go.jp:00048088,
 author = {森, 慎一郎 and 軽部, 雅崇 and 白井, 敏之 and 田尻, 稔 and 竹腰, 琢朗 and 三木, 健太朗 and 白石, ゆりか and 谷本, 克之 and 柴山, 晃一 and 安田, 茂雄 and 山本, 直敬 and 山田, 滋 and 辻, 比呂志 and 野田, 耕司 and 鎌田, 正 and 森 慎一郎 and 軽部 雅崇 and 白井 敏之 and 田尻 稔 and 竹腰 琢朗 and 三木 健太朗 and 白石 ゆりか and 谷本 克之 and 柴山 晃一 and 安田 茂雄 and 山本 直敬 and 山田 滋 and 辻 比呂志 and 野田 耕司 and 鎌田 正},
 issue = {1},
 journal = {International Journal of Radiation Oncology Biology Physics},
 month = {Apr},
 note = {Purpose:Having implemented amplitude-based respiratory gating for scanned carbon-ion beam therapy, we sought to evaluate its effect on positional accuracy and throughput.
Methods and Materials: A total of 10 patients with tumors of the lung and liver partic- ipated in the first clinical trials at our center. Treatment planning was conducted with 4- dimensional computed tomography (4DCT) under free-breathing conditions. The plan- ning target volume (PTV) was calculated by adding a 2- to 3-mm setup margin outside the clinical target volume (CTV) within the gating window. The treatment beam was on when the CTV was within the PTV. Tumor position was detected in real time with a markerless tumor tracking system using paired x-ray fluoroscopic imaging units. Results: The patient setup error (mean ` SD) was 1.1 ` 1.2 mm/0.6 ` 0.4 . The mean internal gating accuracy (95% confidence interval [CI]) was 0.5 mm. If external gating had been applied to this treatment, the mean gating accuracy (95% CI) would have been 4.1 mm. The fluoroscopic radiation doses (mean ` SD) were 23.7 ` 21.8 mGy per beam and less than 487.5 mGy total throughout the treatment course. The setup, prep- aration, and irradiation times (mean ` SD) were 8.9 ` 8.2 min, 9.5 ` 4.6 min, and 4.0 ` 2.4 min, respectively. The treatment room occupation time was 36.7 ` 67.5 min.},
 pages = {258--266},
 title = {Carbon-Ion Pencil Beam Scanning Treatment With Gated Markerless Tumor Tracking: An Analysis of Positional Accuracy},
 volume = {95},
 year = {2016}
}