@article{oai:repo.qst.go.jp:00048073,
 author = {Moriguchi, Sho and Kimura, Yasuyuki and Ichise, Masanori and Arakawa, Ryosuke and Takano, Harumasa and Seki, Chie and Ikoma, Yoko and Takahata, Keisuke and Nagashima, Tomohisa and Yamada, Makiko and Mimura, Masaru and Suhara, Tetsuya and Moriguchi, Sho and Kimura, Yasuyuki and Ichise, Masanori and Arakawa, Ryosuke and Takano, Harumasa and Seki, Chie and Ikoma, Yoko and Takahata, Keisuke and Nagashima, Tomohisa and Yamada, Makiko and Mimura, Masaru and Suhara, Tetsuya},
 issue = {58},
 journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
 month = {Dec},
 note = {Norepinephrine transporter (NET) in the brain plays important roles in human cognition and the pathophysiology of psychiatric disorders. Two radioligands, (S,S)-(11)C-MRB and (S,S)-(18)F-FMeNER-D2, have been used for imaging NETs in the thalamus and midbrain (including locus coeruleus) using positron emission topography (PET) in humans. However, NET density in the equally important cerebral cortex has not been well quantified because of unfavorable kinetics with (S,S)-(11)C-MRB and defluorination with (S,S)-(18)F-FMeNER-D2, which can complicate NET quantification in the cerebral cortex adjacent to the skull containing defluorinated (18)F radioactivity. In this study, we have established analysis methods of quantification of NET density in the brain including cerebral cortex using (S,S)-(18)F-FMeNER-D2 PET.},
 pages = {1140--1145},
 title = {PET quantification of the norepinephrine transporter in human brain with (S,S)-18F-FMeNER-D2.},
 year = {2016}
}