{"created":"2023-05-15T14:37:09.358440+00:00","id":47895,"links":{},"metadata":{"_buckets":{"deposit":"6ea47013-4842-43d5-b181-c376be0a39c1"},"_deposit":{"created_by":1,"id":"47895","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"47895"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00047895","sets":["1"]},"author_link":["480836","480838","480837","480839","480834","480833","480840","480832","480835","480841"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"183","bibliographicPageStart":"180","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"Congenital anomalies"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Growth-retarded mouse (grt/grt) is a spontaneous mutant that is known as an animal model for primary congenital hypothyroidism caused by resistance to TSH signaling. The regional pattern of cerebral cortical hypoplasia was characterized in grt/grt mice. Ex vivo computed tomography (CT)-based volumetry was examined in four regions of the cerebral cortex, i.e., prefrontal, frontal, parietal and occipito-temporal regions, which were demarcated by structural landmarks on coronal CT images. A region-specific reduced volume of the parietal cortical region covering most of the somatosensory cortex was noted in grt/grt mice rather than in both heterozygous (grt/+) and wild-type (+/+) mice. We concluded that the cortical hypoplasia in grt/grt was seen in identical cortical regions corresponding to human congenital hypothyroidism. This article is protected by copyright. All rights reserved.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley on behalf of the Japanese Teratology Society"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"26915353","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/cga.12161","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-3505","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sawada, Kazuhiko"}],"nameIdentifiers":[{"nameIdentifier":"480832","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saito, Shigeyoshi"}],"nameIdentifiers":[{"nameIdentifier":"480833","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugasawa, Akari"}],"nameIdentifiers":[{"nameIdentifier":"480834","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Chika"}],"nameIdentifiers":[{"nameIdentifier":"480835","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoyama, Junya"}],"nameIdentifiers":[{"nameIdentifier":"480836","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohara, Naoko"}],"nameIdentifiers":[{"nameIdentifier":"480837","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Horiuchi-Hirose, Miwa"}],"nameIdentifiers":[{"nameIdentifier":"480838","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"480839","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"齋藤 茂芳","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"480840","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤 千佳","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"480841","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Regional hypoplasia of somatosensory cortex in growth-retarded mice (grt/grt).","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Regional hypoplasia of somatosensory cortex in growth-retarded mice (grt/grt)."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-04-28"},"publish_date":"2017-04-28","publish_status":"0","recid":"47895","relation_version_is_last":true,"title":["Regional hypoplasia of somatosensory cortex in growth-retarded mice (grt/grt)."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:34:21.389300+00:00"}