@article{oai:repo.qst.go.jp:00047782, author = {Koto, Masashi and Hasegawa, Azusa and Takagi, Ryo and Ikawa, Hiroaki and Naganawa, Kensuke and Mizoe, Jun-Etsu and Jingu, Keiichi and Tsujii, Hirohiko and Tsuji, Hiroshi and Kamada, Tadashi and Okamoto, Yoshitaka and 小藤 昌志 and 長谷川 安都佐 and 高木 亮 and 伊川 裕明 and 長縄 憲亮 and 神宮 啓一 and 辻井 博彦 and 辻 比呂志 and 鎌田 正 and 岡本 美孝}, issue = {4}, journal = {Head & neck}, month = {Dec}, note = {Background The purpose of this study was to present our evaluation of the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for locally advanced parotid gland carcinomas. Methods Clinicopathological features and outcomes were evaluated in 46 patients receiving C-ion RT for parotid gland carcinomas. Results Sixteen patients had adenoid cystic carcinoma; 8 had adenocarcinoma, 8 had mucoepidermoid carcinoma, and 14 had other carcinomas. T2, T3, T4a, and T4b diseases were diagnosed in 3, 18, 8, and 17 patients, respectively. C-ion RT was provided to 25 patients as the primary treatment, to 20 patients for local recurrences after surgery, and to 1 patient for residual tumor after surgery. During follow-up (median duration, 62 months), 5-year local control and overall survival (OS) rates were 74.5% and 70.1%, respectively. Of the 30 patients without facial nerve palsy before C-ion RT, 25 showed no radiation-induced facial nerve palsy.}, pages = {724--729}, title = {Definitive carbon-ion radiotherapy for locally advanced parotid gland carcinomas.}, volume = {39}, year = {2016} }