@article{oai:repo.qst.go.jp:00047698,
 author = {Koto, Masashi and Hasegawa, Azusa and Takagi, Ryo and Sasahara, Go and Ikawa, Hiroaki and Mizoe, Jun-Etsu and Jingu, Keiichi and Tsujii, Hirohiko and Kamada, Tadashi and Okamoto, Yoshitaka and 小藤 昌志 and 長谷川 安都佐 and 高木 亮 and 佐々原 剛 and 伊川 裕明 and 溝江 純悦 and 神宮 啓一 and 辻井 博彦 and 鎌田 正 and 岡本 美孝},
 issue = {4},
 journal = {Head & neck},
 month = {Oct},
 note = {Background: The prognosis of advanced squamous cell carcinoma (SCC) of the external auditory canal (EAC) and middle ear (ME) remains poor. Carbon ion radiotherapy (C-ion RT) has shown promise for locally advanced head and neck cancer. Therefore, we evaluated the safety and efficacy of C-ion RT for locally advanced SCC of the EAC and ME. Methods: The cases of 13 patients with advanced (T3 and T4) SCC of the EAC and ME who received C-ion RT as the primary treatment were reviewed. Results: The median follow-up for all patients and the seven surviving patients was 12 and 32 months, respectively. The 1-year and 3-year local control and overall survival rates were 72% and 54% and 70% and 40%, respectively. Severe temporal bone necrosis was observed in two patients. Conclusion: C-ion RT is effective and generally safe for locally advanced SCC of the EAC and ME. Head Neck, 2014.},
 pages = {512--516},
 title = {Carbon ion radiotherapy for locally advanced squamous cell carcinoma of the external auditory canal and middle ear.},
 volume = {38},
 year = {2014}
}