{"created":"2023-05-15T14:37:00.351716+00:00","id":47690,"links":{},"metadata":{"_buckets":{"deposit":"66dc00a0-346c-4111-8963-97a9ab48b0aa"},"_deposit":{"created_by":1,"id":"47690","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"47690"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00047690","sets":["1"]},"author_link":["478526","478517","478528","478520","478527","478524","478530","478531","478521","478518","478522","478523","478525","478519","478529"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"827","bibliographicPageStart":"821","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Nuclear Medicine and Biology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"OBJECTIVE:\n\\nThe goal of this study was to develop an improved (62)Zn/(62)Cu generator based on cation exchange resin and remote preparation at high radioactivity scale for clinical use.\nMETHODS:\n\\nA natural Cu target was irradiated with proton beam in the energy range of 30-->19 MeV at a beam current of 10 muA for 1 h to obtain around 1.7 GBq of (62)Zn. The (62)Zn was isolated from the Cu target on an anion exchange column with more than 97% yield within 2.5 h from the EOB. The (62)Zn/(62)Cu generator was prepared by loading the (62)Zn(2+) on a Sep-Pak plus CM cartridge.\nRESULTS:\n\\nThe generator showed high elution efficiency ( approximately 96%) using a small volume (ca. 3 ml) of a 200-mM glycine solution with a very low breakthrough of (62)Zn (<0.1%).\nCONCLUSIONS:\n\\nThis (62)Zn/(62)Cu generator has been proven to be highly useful as a source of (62)Cu for the synthesis of (62)Cu-labeled compounds. The clinical application of [(62)Cu]Cu-ATSM produced with this generator has been already approved by the Institutional Review Board at the National Institute of Radiological Sciences.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0969-8051","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fukumura, Toshimitsu"}],"nameIdentifiers":[{"nameIdentifier":"478517","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okada, Kazuhiro"}],"nameIdentifiers":[{"nameIdentifier":"478518","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Hisashi"}],"nameIdentifiers":[{"nameIdentifier":"478519","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakao, Ryuji"}],"nameIdentifiers":[{"nameIdentifier":"478520","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mukai, Kensaku"}],"nameIdentifiers":[{"nameIdentifier":"478521","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ferenc, Szelecsenyi"}],"nameIdentifiers":[{"nameIdentifier":"478522","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kovacs, Zoltan"}],"nameIdentifiers":[{"nameIdentifier":"478523","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Kazutoshi"}],"nameIdentifiers":[{"nameIdentifier":"478524","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福村 利光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478525","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 寿","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478526","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中尾 隆士","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478527","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"向井 健作","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478528","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｆｅｒｅｎｃ Ｓｚｅｌｅｃｓｅｎｙｉ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478529","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ゾルタン コバックス","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478530","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 和年","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"478531","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-03-27"},"publish_date":"2017-03-27","publish_status":"0","recid":"47690","relation_version_is_last":true,"title":["An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:36:38.650467+00:00"}