@article{oai:repo.qst.go.jp:00047683,
 author = {Karube, Masataka and Mori, Shinichiro and Tsuji, Hiroshi and Yamamoto, Naoyoshi and Nakajima, Mio and Nakagawa, Keiichi and Kamada, Tadashi and 軽部 雅崇 and 森 慎一郎 and 辻 比呂志 and 山本 直敬 and 中嶋 美緒 and 中川 恵一 and 鎌田 正},
 issue = {5},
 journal = {Journal of radiation research},
 month = {Sep},
 note = {Carbon-ion beam scanning has not previously been used for moving tumor treatments. We have commenced respiratory-gated carbon-ion radiotherapy (CIRT) in the thoracic and abdominal regions under free-breathing conditions as a clinical trial. This study aimed to investigate this treatment in the lungs in comparison with passive scattering CIRT. Five patients had thoracic tumors treated with carbon-ion scanned beams using respiratory gating. We analyzed the actual treatments and calculated passive scattering treatment plans based on the same planning CT. We evaluated tumor size until 3 months post treatment and each treatment plan regarding dose delivered to 95% of the clinical target volume (CTV-D95), mean lung dose, percentage of lung receiving at least 5 Gy (RBE) (Lung-V5), Lung-V10, Lung-V20, heart maximum dose (Dmax), esophagus Dmax, cord Dmax and skin Dmax. Obvious tumor deterioration was not observed up to 3 months post treatment. The dose evaluation metrics were similar item by item between respiratory-gated scanned CIRT and passive scattering CIRT. In conclusion, scanned beam CIRT provided treatments equivalent to passive scattering CIRT for thoracic tumors. Increased sample numbers and longer-term observation are needed.},
 pages = {576--581},
 title = {Carbon-ion pencil beam scanning for thoracic treatment - initiation report and dose metrics evaluation.},
 volume = {57},
 year = {2016}
}