@article{oai:repo.qst.go.jp:00047614, author = {Kameoka, S. and Amako, K. and Iwai, G. and Murakami, K. and Sasaki, T. and Toshito, T. and Yamashita, T. and Aso, T. and Kimura, A. and Kanai, T. and Kanematsu, N. and Komori, M. and Takei, Y. and Yonai, S. and Tashiro, M. and Koikegami, H. and Tomita, H. and Koi, T. and 亀岡 覚 and 尼子 勝哉 and 村上 晃一 and 佐々木 節 and 歳藤 利行 and 金井 達明 and 兼松 伸幸 and 小森 雅孝 and 武井 由佳 and 米内 俊祐 and 田代 睦 and 小池上 一 and 富田 英樹 and 小井 辰巳}, issue = {2}, journal = {Radiological Physics and Technology}, month = {Jul}, note = {We tested the ability of two separate nuclear reaction models, the binary cascade and JQMD (Jaeri version of Quantum Molecular Dynamics), to predict the dose distribution in carbon-ion radiotherapy. This was done by use of a realistic simulation of the experimental irradiation of a water target. Comparison with measurement shows that the binary cascade model does a good job reproducing the spread-out Bragg peak in depth-dose distributions in water irradiated with a 290 MeV/u (per nucleon) beam. However, it significantly overestimates the peak dose for a 400 MeV/u beam. JQMD underestimates the overall dose because of a tendency to break a nucleus into lower-Z fragments than does the binary cascade model. As far as shape of the dose distribution is concerned, JQMD shows fairly good agreement with measurement for both beam energies of 290 and 400 MeV/u, which favors JQMD over the binary cascade model for the calculation of the relative dose distribution in treatment planning.}, pages = {183--187}, title = {Dosimetric evaluation of nuclear interaction models in the Geant4 Monte Carlo simulation toolkit for carbon-ion radiotherapy}, volume = {1}, year = {2008} }